Recent developments in the European and American political landscape highlight the crisis that nowadays characterises transatlantic relations. Questions have emerged about the wave of populism and nationalism that is on the rise in both the US and Europe and its implications for the transatlantic alliance. This report summarises the debate held at the conference “So Faraway, So Close: The Domestic Roots of Transatlantic Crisis” (Rome, 15 April 2019), organised by the Istituto Affari Internazionali and the Friedrich-Ebert-Stiftung. The conference was structured in two sessions, the first on the rise of nationalism and populism in Europe and America, the second on the nationalist-populist threat to transatlantic relations. Report of the conference “So Faraway, So Close: The Domestic Roots of Transatlantic Crisis” organised in Rome on 15 April 2019 by the Istituto Affari Internazionali (IAI) and the Friedrich-Ebert-Stiftung (FES).